Isopropylbenzylamine toxicity. The cell viability was.

Isopropylbenzylamine toxicity. 11. Apr 6, 2010 · IUPAC Standard InChI: InChI=1S/C10H15N/c1-8(2)10-5-3-9(7-11)4-6-10/h3-6,8H,7,11H2,1-2H3 Copy IUPAC Standard InChIKey: YQSHYGCCYVPRDI-UHFFFAOYSA-N Copy CAS Registry Sep 28, 2024 · Product name: N-Isopropylbenzylamine; CBnumber: CB9199936; CAS: 102-97-6; EINECS Number: 203-067-6; Synonyms: Isopropylbenzylamine,N-Isopropylbenzylamine; Relevant identified uses of the substance or mixture and uses advised against. 3–10 mM N-isopropylbenzylamine for 24 hours, and cell viability was measured using MTT assay. Jun 3，2024; N-Isopropylbenzylamine: Application, synthesis and toxicity; N-isopropylbenzylamine, an isomer of methamphetamine, has been used to adulterate methamphetamine, and distributed as fake Aug 22, 2023 · What is n-isopropylbenzylamine? There’s not a lot known about n-isopropylbenzylamine. · Proposition 65 · Chemicals known to cause cancer: Substance is not listed. DrugsData reports that none of the 271 meth samples analyzed between 2019 and 2022 contained N-iso, and shows GC/MS data to support their findings. In this study, in vitro toxicity of isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. The drug is commonly found in four forms: a powder; pills; a sticky base; and the most potent form, crystalline shards, referred to as ice [7,8]. · Section 313 (Specific toxic chemical listings): Substance is not listed. In an attempt to assist in a better understanding of the extent of their use and the fatalities that have been linked to these compounds we present our collated findings in post-mortem and criminal casework where N-Isopropylbenzylamine Revision Date 25-Mar-2024 Hazardous Polymerization Hazardous polymerization does not occur. N-Isopropylbenzylamine (N-iso) is a chemical sometimes blamed for the unpleasant effects of street meth in the US. Sep 1, 2022 · In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. 1016/j. : 102-97-6 1. 2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances Uses advised against : The product is being supplied under the TSCA R&D Exemption The toxicity of N-isopropylbenzylamine was evaluated in SH-SY5Y, PC12, and SN4741 cell lines. Not for medicinal, household or other use. Toxicological information Information on toxicological effects Likely route of exposure Eye contact, Skin contact Acute oral toxicity Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract. Isopropylbenzylamine is a compound that has been used as a diluent or substitute for methamphetamine, but it is not a controlled substance in most jurisdictions. Acute inhalation toxicity In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. Feb 3, 2021 · MA causes toxicity such as liver, brain neurological, cardiovascular, immune system injury, physical, and mental problems (violence, anxiety, and paranoia) [5 – 11]. Use this link for bookmarking this species for future reference. Oct 1, 2022 · Our findings that 1) 2. It’s a structural isomer of meth, meaning it has the same atoms in each molecule, but the atoms are arranged in a different way. Metal. We have found, for the first time, that N-isopropylbenzylamine produced toxicity in cell lines that model neurons. The cell viability was analyzed by using MTT assay after incubation with N-isopropylbenzylamine for 24 h in cells. Feb 1, 2022 · In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. Feb 14, 2024 · In vitro experiments have also demonstrated that N-ipb induces toxicity in neuron-model cell lines. Isopropylbenzylamine is a legal industrial chemical that issometimes used to dilute meth. · Hazardous Air Pollutants Substance is not listed. · Chemicals known to cause reproductive toxicity for females: Substance Apr 6, 2010 · Notice: Concentration information is not available for this spectrum and, therefore, molar absorptivity values cannot be derived. Nov 27, 2019 · N-Isopropylbenzylamine time- and concentration-dependently increases the expression of nNOS, indicate that the toxicity of N-Isopropylbenzylamine might be at least partially via the overproduction of intracellular NO. Sep 23, 2022 · In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. @article{Xu2022NisopropylbenzylamineAM, title={N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro. 4-Isopropylbenzylamine | C10H15N | CID 138221 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological Product name : N-Isopropylbenzylamine Product Number : 136964 Brand : Aldrich CAS-No. The cell viability was [citation needed] [dubious – discuss] The toxicity of N-isopropylbenzylamine has been studied as of 2022 and it has been found to produces toxicity via increasing nitric oxide in vitro. Hazardous Reactions None under normal processing. 2022. · TSCA (Toxic Substances Control Act): Substance is not listed. It has been found to produce toxicity via increasing nitric oxide in vitro, which may be harmful for public health. Relevant identified uses: For R&D use only. What are the effects of n-isopropylbenzylamine? We would like to show you a description here but the site won’t allow us. Figure 1. However, the abuse potential of N -ipb remains unclear. The substances are very chemically similar and caneasily be confusedfor meth. May 10, 2021 · Isopropylbenzylamine. 19 Despite a few clinical evidence and preclinical data, there is currently a lack of preclinical data characterizing the abuse potential of N-ipb. Sep 1, 2022 · DOI: 10. Metals like palladium, lithium and nickelare sometimes used in the meth production process. }, author={Peng Xu and Haijie Li and Qiyang Qiu and Xiao Xiao and Yi Qiu and Xiangyu May 7, 2010 · Other names: Benzylamine, N-isopropyl-; Benzylisopropylamine; Isopropylbenzylamine; N-Benzyl-N-isopropylamine; N-Benzylisopropylamine; N-Isopropylbenzylamine Permanent link for this species. Uses advised against: none. Thus, accurate identification and quantification of MA in the forensic samples is particularly important for investigations and fair trials of drug crimes [ 12 ]. Oct 1, 2019 · N-isopropylbenzylamine, an isomer of methamphetamine, has been used to adulterate methamphetamine, and distributed as fake “Ice” methamphetamine by illicit manufacturers, leading to a world problem of N-isopropylbenzylamine exposure. In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. Oct 1, 2022 · Our main concern in this study is whether and how N-isopropylbenzylamine leads to toxicity, which is critical information for public health and clinical treatment for overdose. Some info suggests that n-iso is used in the making of other chemicals. Toxicological information Acute Toxicity Product Information Component Information Toxicologically Synergistic Products No information available In this study, in vitro toxicity of isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. Traces of these metals can then be found in the final Sep 1, 2013 · The lack of clinical studies on the effects and toxicity of these drugs has made interpretation of toxicological findings difficult. tox. 5 mM N-isopropylbenzylamine significantly increased intracellular NO levels with similar efficacy to that of 5 mM methamphetamine; and 2) N-isopropylbenzylamine time- and concentration-dependently increases the expression of nNOS, indicate that the toxicity of N-isopropylbenzylamine might be at least partially via the N-Isopropylbenzylamine | C10H15N | CID 66024 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities Product name N-Isopropylbenzylamine for synthesis Page 6 of 8 SECTION 11. Cells were treated with 0. In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model The use of methamphetamine is related to abuse, addiction, and toxicity with adverse consequences including cardiovascular problems, paranoia, psychosis, and even mortality [3,5,6]. Information on this page: Notes; Other data available: Phase change data; IR Spectrum The brief introduction of N-isopropylbenzylamine; N-isopropylbenzylamine is originally used as a precursor or intermediate in the chemical industry. Additional Data Feb 14, 2024 · N-Isopropylbenzylamine (N-ipb), a chain isomer of methamphetamine (METH) with similar physical properties, has been used as a substitute for METH in seized drug samples. 153337 Corpus ID: 252500676; N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro.

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